Reflection coefficients of homopore membranes: effect of molecular size and configuration

Osmotic water flow through membranes with uniform defined pores was measured for a variety of macromolecular solutes. Water flow increased linearly with applied hydrostatic pressure, allowing the effective osmotic pressure of the solutes to be estimated by extrapolation. Reflection coefficients for...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1979
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215232/
https://www.ncbi.nlm.nih.gov/pubmed/86597
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collection PubMed
description Osmotic water flow through membranes with uniform defined pores was measured for a variety of macromolecular solutes. Water flow increased linearly with applied hydrostatic pressure, allowing the effective osmotic pressure of the solutes to be estimated by extrapolation. Reflection coefficients for each solute-membrane combination were calculated and correlated with the ratio of solute size to pore size. For the same mean molecular size, proteins were found to have larger reflection coefficients than dextrans. Molecular rigidity may play a role in this difference in behavior.
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spelling pubmed-22152322008-04-23 Reflection coefficients of homopore membranes: effect of molecular size and configuration J Gen Physiol Articles Osmotic water flow through membranes with uniform defined pores was measured for a variety of macromolecular solutes. Water flow increased linearly with applied hydrostatic pressure, allowing the effective osmotic pressure of the solutes to be estimated by extrapolation. Reflection coefficients for each solute-membrane combination were calculated and correlated with the ratio of solute size to pore size. For the same mean molecular size, proteins were found to have larger reflection coefficients than dextrans. Molecular rigidity may play a role in this difference in behavior. The Rockefeller University Press 1979-01-01 /pmc/articles/PMC2215232/ /pubmed/86597 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Reflection coefficients of homopore membranes: effect of molecular size and configuration
title Reflection coefficients of homopore membranes: effect of molecular size and configuration
title_full Reflection coefficients of homopore membranes: effect of molecular size and configuration
title_fullStr Reflection coefficients of homopore membranes: effect of molecular size and configuration
title_full_unstemmed Reflection coefficients of homopore membranes: effect of molecular size and configuration
title_short Reflection coefficients of homopore membranes: effect of molecular size and configuration
title_sort reflection coefficients of homopore membranes: effect of molecular size and configuration
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215232/
https://www.ncbi.nlm.nih.gov/pubmed/86597

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