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Reduced Lung Function in a Chronic Asthma Model Is Associated with Prolonged Inflammation, but Independent of Peribronchial Fibrosis

BACKGROUND: In asthma, mechanisms contributing to chronicity remain to be determined. Recent models of sensitisation with prolonged airway allergen challenges reproduce typical features of chronic asthma. However, the interplay between inflammation, structural changes and lung function is poorly und...

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Detalles Bibliográficos
Autores principales:	Koerner-Rettberg, Cordula, Doths, Sandra, Stroet, Anke, Schwarze, Jürgen
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215329/ https://www.ncbi.nlm.nih.gov/pubmed/18253511 http://dx.doi.org/10.1371/journal.pone.0001575

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