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Osmotic water permeability of human red cells
The osmotic water permeability of human red cells has been reexamined with a stopped-flow device and a new perturbation technique. Small osmotic gradients are used to minimize the systematic error caused by nonlinearities in the relationship between cell volume and light scattering. Corrections are...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1981
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215438/ https://www.ncbi.nlm.nih.gov/pubmed/7229611 |
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collection | PubMed |
description | The osmotic water permeability of human red cells has been reexamined with a stopped-flow device and a new perturbation technique. Small osmotic gradients are used to minimize the systematic error caused by nonlinearities in the relationship between cell volume and light scattering. Corrections are then made for residual systematic error. Our results show that the hydraulic conductivity, Lp, is essentially independent of the direction of water flow and of osmolality in the range 184-365 mosM. the mean value of Lp obtained obtained was 1.8 +/- 0.1 (SEM) X 10-11 cm3 dyne -1 s-1. |
format | Text |
id | pubmed-2215438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1981 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22154382008-04-23 Osmotic water permeability of human red cells J Gen Physiol Articles The osmotic water permeability of human red cells has been reexamined with a stopped-flow device and a new perturbation technique. Small osmotic gradients are used to minimize the systematic error caused by nonlinearities in the relationship between cell volume and light scattering. Corrections are then made for residual systematic error. Our results show that the hydraulic conductivity, Lp, is essentially independent of the direction of water flow and of osmolality in the range 184-365 mosM. the mean value of Lp obtained obtained was 1.8 +/- 0.1 (SEM) X 10-11 cm3 dyne -1 s-1. The Rockefeller University Press 1981-05-01 /pmc/articles/PMC2215438/ /pubmed/7229611 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Osmotic water permeability of human red cells |
title | Osmotic water permeability of human red cells |
title_full | Osmotic water permeability of human red cells |
title_fullStr | Osmotic water permeability of human red cells |
title_full_unstemmed | Osmotic water permeability of human red cells |
title_short | Osmotic water permeability of human red cells |
title_sort | osmotic water permeability of human red cells |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215438/ https://www.ncbi.nlm.nih.gov/pubmed/7229611 |