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In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint
BACKGROUND: The Mitotic Spindle Assembly Checkpoint ((M)SAC) is an evolutionary conserved mechanism that ensures the correct segregation of chromosomes by restraining cell cycle progression from entering anaphase until all chromosomes have made proper bipolar attachments to the mitotic spindle. Its...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2215771/ https://www.ncbi.nlm.nih.gov/pubmed/18253502 http://dx.doi.org/10.1371/journal.pone.0001555 |