Cargando…

Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines

BACKGROUND: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The non-synonymous SNPs (nsSNPs) that lead to amino acid changes in the protein product may account for nearly half of the know...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Jian, Wu, Ningfeng, Guo, Xuexia, Guo, Jun, Zhang, Juhua, Fan, Yunliu
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216041/ https://www.ncbi.nlm.nih.gov/pubmed/18005451 http://dx.doi.org/10.1186/1471-2105-8-450

Ejemplares similares

Prediction of amyloid fibril-forming segments based on a support vector machine
por: Tian, Jian, et al.
Publicado: (2009)

Predicting changes in protein thermostability brought about by single- or multi-site mutations
por: Tian, Jian, et al.
Publicado: (2010)

Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli
por: Tian, Jian, et al.
Publicado: (2017)

SMOQ: a tool for predicting the absolute residue-specific quality of a single protein model with support vector machines
por: Cao, Renzhi, et al.
Publicado: (2014)

A flexible tool to plot a genomic map for single nucleotide polymorphisms
por: Zhang, Fuquan
Publicado: (2016)

miTarget: microRNA target gene prediction using a support vector machine
por: Kim, Sung-Kyu, et al.
Publicado: (2006)

Strand bias in complementary single-nucleotide polymorphisms of transcribed human sequences: evidence for functional effects of synonymous polymorphisms
por: Qu, Hui-Qi, et al.
Publicado: (2006)

Software for tag single nucleotide polymorphism selection
por: Stram, Daniel O
Publicado: (2005)

MICO: A meta-tool for prediction of the effects of non-synonymous mutations
por: Lee, Gilliean, et al.
Publicado: (2014)

SNPchiMp v.3: integrating and standardizing single nucleotide polymorphism data for livestock species
por: Nicolazzi, Ezequiel L, et al.
Publicado: (2015)

GAPscreener: An automatic tool for screening human genetic association literature in PubMed using the support vector machine technique
por: Yu, Wei, et al.
Publicado: (2008)

ShinyCore: An R/Shiny program for establishing core collection based on single nucleotide polymorphism data
por: Kim, Steven, et al.
Publicado: (2023)

Ranking non-synonymous single nucleotide polymorphisms based on disease concepts
por: Shihab, Hashem A, et al.
Publicado: (2014)

scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis
por: Wong, John K. L., et al.
Publicado: (2023)

QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyploid species
por: Tang, Jifeng, et al.
Publicado: (2006)

SNUFER: A software for localization and presentation of single nucleotide polymorphisms using a Clustal multiple sequence alignment output file
por: Mansur, Marco A B, et al.
Publicado: (2008)

The Effect of Synonymous Single-Nucleotide Polymorphisms on an Atypical Cystic Fibrosis Clinical Presentation
por: Bampi, Giovana B., et al.
Publicado: (2020)

Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
por: Hu, Jing, et al.
Publicado: (2008)

Human Coding Synonymous Single Nucleotide Polymorphisms at Ramp Regions of mRNA Translation
por: Li, Quan, et al.
Publicado: (2013)

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene
por: Dakal, Tikam Chand, et al.
Publicado: (2017)

SomatoSim: precision simulation of somatic single nucleotide variants
por: Hawari, Marwan A., et al.
Publicado: (2021)

Identification of the Transcriptional Regulator NcrB in the Nickel Resistance Determinant of Leptospirillum ferriphilum UBK03
por: Zhu, Tao, et al.
Publicado: (2011)

PCAN: phenotype consensus analysis to support disease-gene association
por: Godard, Patrice, et al.
Publicado: (2016)

T-RFPred: a nucleotide sequence size prediction tool for microbial community description based on terminal-restriction fragment length polymorphism chromatograms
por: Fernàndez-Guerra, Antonio, et al.
Publicado: (2010)

SNVHMM: predicting single nucleotide variants from next generation sequencing
por: Bian, Jiawen, et al.
Publicado: (2013)

Association of non-synonymous single nucleotide polymorphisms in the LOXL1 gene with pseudoexfoliation syndrome in India
por: Ramprasad, Vedam Lakshmi, et al.
Publicado: (2008)

Non-Synonymous Single-Nucleotide Polymorphisms and Physical Activity Interactions on Adiposity Parameters in Malaysian Adolescents
por: Zaharan, Nur Lisa, et al.
Publicado: (2018)

Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
por: Brodie, Ryan, et al.
Publicado: (2004)

BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms
por: Mueller, Sabine C., et al.
Publicado: (2015)

Prediction of the Damage-Associated Non-Synonymous Single Nucleotide Polymorphisms in the Human MC1R Gene
por: Hepp, Diego, et al.
Publicado: (2015)

A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia
por: Rodden, Layne N., et al.
Publicado: (2022)

Annotate-it: a Swiss-knife approach to annotation, analysis and interpretation of single nucleotide variation in human disease
por: Sifrim, Alejandro, et al.
Publicado: (2012)

Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads
por: Prada-Luengo, Iñigo, et al.
Publicado: (2019)

MAC: identifying and correcting annotation for multi-nucleotide variations
por: Wei, Lei, et al.
Publicado: (2015)

A single synonymous nucleotide change impacts the male-killing phenotype of prophage WO gene wmk
por: Perlmutter, Jessamyn I, et al.
Publicado: (2021)

MegaR: an interactive R package for rapid sample classification and phenotype prediction using metagenome profiles and machine learning
por: Dhungel, Eliza, et al.
Publicado: (2021)

Synonymous nucleotide changes drive papillomavirus evolution
por: King, Kelly M., et al.
Publicado: (2022)

Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms
por: Cheng, Tammy M. K., et al.
Publicado: (2008)

A Non-Synonymous Single Nucleotide Polymorphism in the HJURP Gene Associated with Susceptibility to Hepatocellular Carcinoma among Chinese
por: Huang, Wenfeng, et al.
Publicado: (2016)

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis
por: Ogun, Oluwamayowa Joshua, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8i4199d22t0ueoe6uq7dn3rsc8