Phase 1 Study of a Combination AMA1 Blood Stage Malaria Vaccine in Malian Children

BACKGROUND: Apical Membrane Antigen-1 (AMA1) is one of the leading blood stage malaria vaccine candidates. AMA1-C1/Alhydrogel® consists of an equal mixture of recombinant AMA1 from FVO and 3D7 clones of P. falciparum, adsorbed onto Alhydrogel®. A Phase 1 study in semi-immune adults in Mali showed th...

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Detalles Bibliográficos
Autores principales: Dicko, Alassane, Sagara, Issaka, Ellis, Ruth D., Miura, Kazutoyo, Guindo, Ousmane, Kamate, Beh, Sogoba, Moussa, Niambelé, Mohamed Balla, Sissoko, Mady, Baby, Mounirou, Dolo, Amagana, Mullen, Gregory E. D., Fay, Michael P., Pierce, Mark, Diallo, Dapa A., Saul, Allan, Miller, Louis H., Doumbo, Ogobara K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216433/
https://www.ncbi.nlm.nih.gov/pubmed/18270560
http://dx.doi.org/10.1371/journal.pone.0001563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216433/
https://www.ncbi.nlm.nih.gov/pubmed/18270560
http://dx.doi.org/10.1371/journal.pone.0001563

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