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Selective Pharmacological Targeting of a DEAD Box RNA Helicase

RNA helicases represent a large family of proteins implicated in many biological processes including ribosome biogenesis, splicing, translation and mRNA degradation. However, these proteins have little substrate specificity, making inhibition of selected helicases a challenging problem. The prototyp...

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Detalles Bibliográficos
Autores principales:	Lindqvist, Lisa, Oberer, Monika, Reibarkh, Mikhail, Cencic, Regina, Bordeleau, Marie-Eve, Vogt, Emily, Marintchev, Assen, Tanaka, Junichi, Fagotto, Francois, Altmann, Michael, Wagner, Gerhard, Pelletier, Jerry
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216682/ https://www.ncbi.nlm.nih.gov/pubmed/18270573 http://dx.doi.org/10.1371/journal.pone.0001583

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