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Phase I Trial of an Alhydrogel Adjuvanted Hepatitis B Core Virus-Like Particle Containing Epitopes of Plasmodium falciparum Circumsporozoite Protein

The objectives of this non-randomized, non-blinded, dose-escalating Phase I clinical trial were to assess the safety, reactogenicity and immunogenicity of ICC-1132 formulated with Alhydrogel (aluminum hydroxide) in 51 healthy, malaria-naive adults aged 18 to 45 years. ICC-1132 (Malariavax) is a reco...

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Detalles Bibliográficos
Autores principales:	Gregson, Aric L., Oliveira, Giane, Othoro, Caroline, Calvo-Calle, J. Mauricio, Thorton, George B., Nardin, Elizabeth, Edelman, Robert
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2216688/ https://www.ncbi.nlm.nih.gov/pubmed/18253503 http://dx.doi.org/10.1371/journal.pone.0001556

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