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Role of Transmembrane Segment S5 on Gating of Voltage-dependent K(+) Channels

The cytoplasmic half of S5 (5′S5) has been identified as part of the inner mouth of the pore based on evidence that mutations in this region greatly alter single channel conductance, 4-aminopyridine (4-AP) block and the rate of channel closing upon repolarization (deactivation). The latter effect, s...

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Detalles Bibliográficos
Autores principales: Shieh, Char-Chang, Klemic, Kathryn G., Kirsch, Glenn E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217039/
https://www.ncbi.nlm.nih.gov/pubmed/9222902

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