Trapping of Organic Blockers by Closing of Voltage-dependent K(+) Channels : Evidence for a Trap Door Mechanism of Activation Gating

Small organic molecules, like quaternary ammonium compounds, have long been used to probe both the permeation and gating of voltage-dependent K(+) channels. For most K(+) channels, intracellularly applied quaternary ammonium (QA) compounds such as tetraethylammonium (TEA) and decyltriethylammonium (...

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Detalles Bibliográficos
Autores principales: Holmgren, Miguel, Smith, Paula L., Yellen, Gary
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217058/
https://www.ncbi.nlm.nih.gov/pubmed/9154902

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