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Molecular Analysis of the Putative Inactivation Particle in the Inactivation Gate of Brain Type IIA Na(+) Channels
Fast Na(+) channel inactivation is thought to involve binding of phenylalanine 1489 in the hydrophobic cluster IFM in L(III-IV )of the rat brain type IIA Na(+) channel. We have analyzed macroscopic and single channel currents from Na(+) channels with mutations within and adjacent to hydrophobic clus...
Autores principales: | Kellenberger, Stephan, West, James W., Scheuer, Todd, Catterall, William A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217064/ https://www.ncbi.nlm.nih.gov/pubmed/9154906 |
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