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Molecular Analysis of Potential Hinge Residues in the Inactivation Gate of Brain Type IIA Na(+) Channels
During inactivation of Na(+) channels, the intracellular loop connecting domains III and IV is thought to fold into the channel protein and occlude the pore through interaction of the hydrophobic motif isoleucine-phenylalanine-methionine (IFM) with a receptor site. We have searched for amino acid re...
Autores principales: | Kellenberger, Stephan, West, James W., Catterall, William A., Scheuer, Todd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217067/ https://www.ncbi.nlm.nih.gov/pubmed/9154907 |
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