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Uncharged S4 Residues and Cooperativity in Voltage-dependent Potassium Channel Activation

Substitution of the S4 of Shaw into Shaker alters cooperativity in channel activation by slowing a cooperative transition late in the activation pathway. To determine the amino acids responsible for the functional changes in Shaw S4, we created several mutants by substituting amino acids from Shaw S...

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Detalles Bibliográficos
Autores principales: Smith-Maxwell, Catherine J., Ledwell, Jennifer L., Aldrich, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217114/
https://www.ncbi.nlm.nih.gov/pubmed/9482709

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