Gating of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels by Adenosine Triphosphate Hydrolysis : Quantitative Analysis of a Cyclic Gating Scheme

Gating of the cystic fibrosis transmembrane conductance regulator (CFTR) involves a coordinated action of ATP on two nucleotide binding domains (NBD1 and NBD2). Previous studies using nonhydrolyzable ATP analogues and NBD mutant CFTR have suggested that nucleotide hydrolysis at NBD1 is required for...

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Detalles Bibliográficos
Autores principales: Zeltwanger, Shawn, Wang, Fei, Wang, Guo-Tang, Gillis, Kevin D., Hwang, Tzyh-Chang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217165/
https://www.ncbi.nlm.nih.gov/pubmed/10102935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217165/
https://www.ncbi.nlm.nih.gov/pubmed/10102935

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