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Human Ether-à-go-go–related Gene K(+) Channel Gating Probed with Extracellular Ca(2+) : Evidence for Two Distinct Voltage Sensors

Human ether-à-go-go–related gene (HERG) encoded K(+) channels were expressed in Chinese hamster ovary (CHO-K1) cells and studied by whole-cell voltage clamp in the presence of varied extracellular Ca(2+) concentrations and physiological external K(+). Elevation of external Ca(2+) from 1.8 to 10 mM r...

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Detalles Bibliográficos
Autores principales: Johnson, J.P., Mullins, Franklin M., Bennett, Paul B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217168/
https://www.ncbi.nlm.nih.gov/pubmed/10102937