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Modulation of the Shaker K(+)Channel Gating Kinetics by the S3–S4 Linker

In Shaker K(+) channels depolarization displaces outwardly the positively charged residues of the S4 segment. The amount of this displacement is unknown, but large movements of the S4 segment should be constrained by the length and flexibility of the S3–S4 linker. To investigate the role of the S3–S...

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Detalles Bibliográficos
Autores principales: Gonzalez, Carlos, Rosenman, Eduardo, Bezanilla, Francisco, Alvarez, Osvaldo, Latorre, Ramon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217197/
https://www.ncbi.nlm.nih.gov/pubmed/10653896