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Nicotinic Receptor Fourth Transmembrane Domain: Hydrogen Bonding by Conserved Threonine Contributes to Channel Gating Kinetics

The fourth transmembrane domain (M4) of the nicotinic acetylcholine receptor (AChR) contributes to the kinetics of activation, yet its close association with the lipid bilayer makes it the outermost of the transmembrane domains. To investigate mechanistic and structural contributions of M4 to AChR a...

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Detalles Bibliográficos
Autores principales:	Bouzat, Cecilia, Barrantes, Francisco, Sine, Steven
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217218/ https://www.ncbi.nlm.nih.gov/pubmed/10779322

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