Allosteric Regulation of Na/Ca Exchange Current by Cytosolic Ca in Intact Cardiac Myocytes

The cardiac sarcolemmal Na-Ca exchanger (NCX) is allosterically regulated by [Ca](i) such that when [Ca](i) is low, NCX current (I(NCX)) deactivates. In this study, we used membrane potential (E(m)) and I(NCX) to control Ca entry into and Ca efflux from intact cardiac myocytes to investigate whether...

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Detalles Bibliográficos
Autores principales: Weber, Christopher R., Ginsburg, Kenneth S., Philipson, Kenneth D., Shannon, Thomas R., Bers, Donald M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217247/
https://www.ncbi.nlm.nih.gov/pubmed/11158165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217247/
https://www.ncbi.nlm.nih.gov/pubmed/11158165

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