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Involvement of Helices at the Dimer Interface in ClC-1 Common Gating
ClC-1 is a dimeric, double-pored chloride channel that is present in skeletal muscle. Mutations of this channel can result in the condition myotonia, a muscle disorder involving increased muscle stiffness. It has been shown that the dominant form of myotonia often results from mutations that affect...
Autores principales: | Duffield, Michael, Rychkov, Grigori, Bretag, Allan, Roberts, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217322/ https://www.ncbi.nlm.nih.gov/pubmed/12566541 http://dx.doi.org/10.1085/jgp.20028741 |
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