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Titin Determines the Frank-Starling Relation in Early Diastole

Titin, a giant protein spanning half the sarcomere, is responsible for passive and restoring forces in cardiac myofilaments during sarcomere elongation and compression, respectively. In addition, titin has been implicated in the length-dependent activation that occurs in the stretched sarcomere, dur...

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Detalles Bibliográficos
Autores principales: Helmes, Michiel, Lim, Chee Chew, Liao, Ronglih, Bharti, Ajit, Cui, Lei, Sawyer, Douglas B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217323/
https://www.ncbi.nlm.nih.gov/pubmed/12566538
http://dx.doi.org/10.1085/jgp.20028652