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Titin Determines the Frank-Starling Relation in Early Diastole
Titin, a giant protein spanning half the sarcomere, is responsible for passive and restoring forces in cardiac myofilaments during sarcomere elongation and compression, respectively. In addition, titin has been implicated in the length-dependent activation that occurs in the stretched sarcomere, dur...
Autores principales: | Helmes, Michiel, Lim, Chee Chew, Liao, Ronglih, Bharti, Ajit, Cui, Lei, Sawyer, Douglas B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217323/ https://www.ncbi.nlm.nih.gov/pubmed/12566538 http://dx.doi.org/10.1085/jgp.20028652 |
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