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Influence of Pore Residues on Permeation Properties in the Kv2.1 Potassium Channel. Evidence for a Selective Functional Interaction of K(+) with the Outer Vestibule

The Kv2.1 potassium channel contains a lysine in the outer vestibule (position 356) that markedly reduces open channel sensitivity to changes in external [K(+)]. To investigate the mechanism underlying this effect, we examined the influence of this outer vestibule lysine on three measures of K(+) an...

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Detalles Bibliográficos
Autores principales: Consiglio, Joseph F., Andalib, Payam, Korn, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217329/
https://www.ncbi.nlm.nih.gov/pubmed/12566539
http://dx.doi.org/10.1085/jgp.20028756

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