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Single Channel Function of Inositol 1,4,5-trisphosphate Receptor Type-1 and -2 Isoform Domain-Swap Chimeras
The InsP(3)R proteins have three recognized domains, the InsP(3)-binding, regulatory/coupling, and channel domains (Mignery, G.A., and T.C. Südhof. 1990. EMBO J. 9:3893–3898). The InsP(3) binding domain and the channel-forming domain are at opposite ends of the protein. Ligand regulation of the chan...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217376/ https://www.ncbi.nlm.nih.gov/pubmed/12695486 http://dx.doi.org/10.1085/jgp.200208718 |