The Na(+) Channel Inactivation Gate Is a Molecular Complex: A Novel Role of the COOH-terminal Domain

Electrical activity in nerve, skeletal muscle, and heart requires finely tuned activity of voltage-gated Na(+) channels that open and then enter a nonconducting inactivated state upon depolarization. Inactivation occurs when the gate, the cytoplasmic loop linking domains III and IV of the α subunit,...

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Detalles Bibliográficos
Autores principales: Motoike, Howard K., Liu, Huajun, Glaaser, Ian W., Yang, An-Suei, Tateyama, Michihiro, Kass, Robert S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217430/
https://www.ncbi.nlm.nih.gov/pubmed/14744988
http://dx.doi.org/10.1085/jgp.200308929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217430/
https://www.ncbi.nlm.nih.gov/pubmed/14744988
http://dx.doi.org/10.1085/jgp.200308929

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