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Regulation of K(ir) Channels by Intracellular pH and Extracellular K(+) : Mechanisms of Coupling
ROMK channels are regulated by internal pH (pH(i)) and extracellular K(+) (K(+) (o)). The mechanisms underlying this regulation were studied in these channels after expression in Xenopus oocytes. Replacement of the COOH-terminal portion of ROMK2 (Kir1.1b) with the corresponding region of the pH-inse...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217465/ https://www.ncbi.nlm.nih.gov/pubmed/15051808 http://dx.doi.org/10.1085/jgp.200308989 |