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Functional Roles of Nonconserved Structural Segments in CFTR's NH(2)-terminal Nucleotide Binding Domain
The cystic fibrosis transmembrane conductance regulator (CFTR), encoded by the gene mutated in cystic fibrosis patients, belongs to the family of ATP-binding cassette (ABC) proteins, but, unlike other members, functions as a chloride channel. CFTR is activated by protein kinase A (PKA)-mediated phos...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217481/ https://www.ncbi.nlm.nih.gov/pubmed/15596536 http://dx.doi.org/10.1085/jgp.200409174 |