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Conduction through the Inward Rectifier Potassium Channel, Kir2.1, Is Increased by Negatively Charged Extracellular Residues

Ion channel conductance can be influenced by electrostatic effects originating from fixed “surface” charges that are remote from the selectivity filter. To explore whether surface charges contribute to the conductance properties of Kir2.1 channels, unitary conductance was measured in cell-attached r...

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Detalles Bibliográficos
Autores principales:	D'Avanzo, Nazzareno, Cho, Hee Cheol, Tolokh, Illya, Pekhletski, Roman, Tolokh, Igor, Gray, Chris, Goldman, Saul, Backx, Peter H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217506/ https://www.ncbi.nlm.nih.gov/pubmed/15824191 http://dx.doi.org/10.1085/jgp.200409175

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