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Effects of arachidonic acid supplementation on training adaptations in resistance-trained males
BACKGROUND: To determine the impact of AA supplementation during resistance training on body composition, training adaptations, and markers of muscle hypertrophy in resistance-trained males. METHODS: In a randomized and double blind manner, 31 resistance-trained male subjects (22.1 ± 5.0 years, 180...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217562/ https://www.ncbi.nlm.nih.gov/pubmed/18045476 http://dx.doi.org/10.1186/1550-2783-4-21 |
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author | Roberts, Michael D Iosia, Mike Kerksick, Chad M Taylor, Lem W Campbell, Bill Wilborn, Colin D Harvey, Travis Cooke, Matthew Rasmussen, Chris Greenwood, Mike Wilson, Ronald Jitomir, Jean Willoughby, Darryn Kreider, Richard B |
author_facet | Roberts, Michael D Iosia, Mike Kerksick, Chad M Taylor, Lem W Campbell, Bill Wilborn, Colin D Harvey, Travis Cooke, Matthew Rasmussen, Chris Greenwood, Mike Wilson, Ronald Jitomir, Jean Willoughby, Darryn Kreider, Richard B |
author_sort | Roberts, Michael D |
collection | PubMed |
description | BACKGROUND: To determine the impact of AA supplementation during resistance training on body composition, training adaptations, and markers of muscle hypertrophy in resistance-trained males. METHODS: In a randomized and double blind manner, 31 resistance-trained male subjects (22.1 ± 5.0 years, 180 ± 0.1 cm, 86.1 ± 13.0 kg, 18.1 ± 6.4% body fat) ingested either a placebo (PLA: 1 g·day(-1 )corn oil, n = 16) or AA (AA: 1 g·day(-1 )AA, n = 15) while participating in a standardized 4 day·week(-1 )resistance training regimen. Fasting blood samples, body composition, bench press one-repetition maximum (1RM), leg press 1RM and Wingate anaerobic capacity sprint tests were completed after 0, 25, and 50 days of supplementation. Percutaneous muscle biopsies were taken from the vastus lateralis on days 0 and 50. RESULTS: Wingate relative peak power was significantly greater after 50 days of supplementation while the inflammatory cytokine IL-6 was significantly lower after 25 days of supplementation in the AA group. PGE(2 )levels tended to be greater in the AA group. However, no statistically significant differences were observed between groups in body composition, strength, anabolic and catabolic hormones, or markers of muscle hypertrophy (i.e. total protein content or MHC type I, IIa, and IIx protein content) and other intramuscular markers (i.e. FP and EP(3 )receptor density or MHC type I, IIa, and IIx mRNA expression). CONCLUSION: AA supplementation during resistance-training may enhance anaerobic capacity and lessen the inflammatory response to training. However, AA supplementation did not promote statistically greater gains in strength, muscle mass, or influence markers of muscle hypertrophy. |
format | Text |
id | pubmed-2217562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-22175622008-01-30 Effects of arachidonic acid supplementation on training adaptations in resistance-trained males Roberts, Michael D Iosia, Mike Kerksick, Chad M Taylor, Lem W Campbell, Bill Wilborn, Colin D Harvey, Travis Cooke, Matthew Rasmussen, Chris Greenwood, Mike Wilson, Ronald Jitomir, Jean Willoughby, Darryn Kreider, Richard B J Int Soc Sports Nutr Research Article BACKGROUND: To determine the impact of AA supplementation during resistance training on body composition, training adaptations, and markers of muscle hypertrophy in resistance-trained males. METHODS: In a randomized and double blind manner, 31 resistance-trained male subjects (22.1 ± 5.0 years, 180 ± 0.1 cm, 86.1 ± 13.0 kg, 18.1 ± 6.4% body fat) ingested either a placebo (PLA: 1 g·day(-1 )corn oil, n = 16) or AA (AA: 1 g·day(-1 )AA, n = 15) while participating in a standardized 4 day·week(-1 )resistance training regimen. Fasting blood samples, body composition, bench press one-repetition maximum (1RM), leg press 1RM and Wingate anaerobic capacity sprint tests were completed after 0, 25, and 50 days of supplementation. Percutaneous muscle biopsies were taken from the vastus lateralis on days 0 and 50. RESULTS: Wingate relative peak power was significantly greater after 50 days of supplementation while the inflammatory cytokine IL-6 was significantly lower after 25 days of supplementation in the AA group. PGE(2 )levels tended to be greater in the AA group. However, no statistically significant differences were observed between groups in body composition, strength, anabolic and catabolic hormones, or markers of muscle hypertrophy (i.e. total protein content or MHC type I, IIa, and IIx protein content) and other intramuscular markers (i.e. FP and EP(3 )receptor density or MHC type I, IIa, and IIx mRNA expression). CONCLUSION: AA supplementation during resistance-training may enhance anaerobic capacity and lessen the inflammatory response to training. However, AA supplementation did not promote statistically greater gains in strength, muscle mass, or influence markers of muscle hypertrophy. BioMed Central 2007-11-28 /pmc/articles/PMC2217562/ /pubmed/18045476 http://dx.doi.org/10.1186/1550-2783-4-21 Text en Copyright © 2007 Roberts et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Roberts, Michael D Iosia, Mike Kerksick, Chad M Taylor, Lem W Campbell, Bill Wilborn, Colin D Harvey, Travis Cooke, Matthew Rasmussen, Chris Greenwood, Mike Wilson, Ronald Jitomir, Jean Willoughby, Darryn Kreider, Richard B Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title | Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title_full | Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title_fullStr | Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title_full_unstemmed | Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title_short | Effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
title_sort | effects of arachidonic acid supplementation on training adaptations in resistance-trained males |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217562/ https://www.ncbi.nlm.nih.gov/pubmed/18045476 http://dx.doi.org/10.1186/1550-2783-4-21 |
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