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Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay

Pulse vaccination, the repeated application of vaccine over a defined age range, is gaining prominence as an effective strategy for the elimination of infectious diseases. An SIR epidemic model with pulse vaccination and distributed time delay is proposed in this paper. Using the discrete dynamical...

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Detalles Bibliográficos
Autores principales: Gao, Shujing, Teng, Zhidong, Nieto, Juan J., Torres, Angela
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217597/
https://www.ncbi.nlm.nih.gov/pubmed/18322563
http://dx.doi.org/10.1155/2007/64870
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author Gao, Shujing
Teng, Zhidong
Nieto, Juan J.
Torres, Angela
author_facet Gao, Shujing
Teng, Zhidong
Nieto, Juan J.
Torres, Angela
author_sort Gao, Shujing
collection PubMed
description Pulse vaccination, the repeated application of vaccine over a defined age range, is gaining prominence as an effective strategy for the elimination of infectious diseases. An SIR epidemic model with pulse vaccination and distributed time delay is proposed in this paper. Using the discrete dynamical system determined by the stroboscopic map, we obtain the exact infection-free periodic solution of the impulsive epidemic system and prove that the infection-free periodic solution is globally attractive if the vaccination rate is larger enough. Moreover, we show that the disease is uniformly persistent if the vaccination rate is less than some critical value. The permanence of the model is investigated analytically. Our results indicate that a large pulse vaccination rate is sufficient for the eradication of the disease.
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spelling pubmed-22175972008-03-05 Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay Gao, Shujing Teng, Zhidong Nieto, Juan J. Torres, Angela J Biomed Biotechnol Research Article Pulse vaccination, the repeated application of vaccine over a defined age range, is gaining prominence as an effective strategy for the elimination of infectious diseases. An SIR epidemic model with pulse vaccination and distributed time delay is proposed in this paper. Using the discrete dynamical system determined by the stroboscopic map, we obtain the exact infection-free periodic solution of the impulsive epidemic system and prove that the infection-free periodic solution is globally attractive if the vaccination rate is larger enough. Moreover, we show that the disease is uniformly persistent if the vaccination rate is less than some critical value. The permanence of the model is investigated analytically. Our results indicate that a large pulse vaccination rate is sufficient for the eradication of the disease. Hindawi Publishing Corporation 2007 2007-10-10 /pmc/articles/PMC2217597/ /pubmed/18322563 http://dx.doi.org/10.1155/2007/64870 Text en Copyright © 2007 Shujing Gao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Gao, Shujing
Teng, Zhidong
Nieto, Juan J.
Torres, Angela
Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title_full Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title_fullStr Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title_full_unstemmed Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title_short Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay
title_sort analysis of an sir epidemic model with pulse vaccination and distributed time delay
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217597/
https://www.ncbi.nlm.nih.gov/pubmed/18322563
http://dx.doi.org/10.1155/2007/64870
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