Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calcium

Single batrachotoxin-activated sodium channels from rat brain were modified by trimethyloxonium (TMO) after incorporation in planar lipid bilayers. TMO modification eliminated saxitoxin (STX) sensitivity, reduced the single channel conductance by 37%, and reduced calcium block of inward sodium curre...

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Detalles Bibliográficos
Autores principales: Worley JF, French, RJ, Krueger, BK
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1986
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217599/
https://www.ncbi.nlm.nih.gov/pubmed/2419487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217599/
https://www.ncbi.nlm.nih.gov/pubmed/2419487

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