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RGD-avidin–biotin pretargeting to α(v)β(3) integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand (TRAIL)

Recombinant TNF-related apoptosis-inducing ligand (TRAIL) is considered a powerful and selective inducer of tumor cell death. We hypothesize that TRAIL’s potential as anticancer agent can be enhanced further by promoting its accumulation in tumor tissue. For this purpose, we developed TRAIL complexe...

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Detalles Bibliográficos
Autores principales:	Tarrus, Marc, van der Sloot, Almer M., Temming, Kai, Lacombe, Marie, Opdam, Frank, Quax, Wim J., Molema, Grietje, Poelstra, Klaas, Kok, Robbert J.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer US 2007
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217618/ https://www.ncbi.nlm.nih.gov/pubmed/18071905 http://dx.doi.org/10.1007/s10495-007-0166-5

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