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Deuterium Isotope Effects on Permeation and Gating of Proton Channels in Rat Alveolar Epithelium

The voltage-activated H(+) selective conductance of rat alveolar epithelial cells was studied using whole-cell and excised-patch voltage-clamp techniques. The effects of substituting deuterium oxide, D(2)O, for water, H(2)O, on both the conductance and the pH dependence of gating were explored. D(+)...

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Detalles Bibliográficos
Autores principales: DeCoursey, Thomas E., Cherny, Vladimir V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219434/
https://www.ncbi.nlm.nih.gov/pubmed/9101402