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NMR spectroscopic and analytical ultracentrifuge analysis of membrane protein detergent complexes

BACKGROUND: Structural studies of integral membrane proteins (IMPs) are hampered by inherent difficulties in their heterologous expression and in the purification of solubilized protein-detergent complexes (PDCs). The choice and concentrations of detergents used in an IMP preparation play a critical...

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Detalles Bibliográficos
Autores principales: Maslennikov, Innokentiy, Kefala, Georgia, Johnson, Casey, Riek, Roland, Choe, Senyon, Kwiatkowski, Witek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219997/
https://www.ncbi.nlm.nih.gov/pubmed/17988403
http://dx.doi.org/10.1186/1472-6807-7-74

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