Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice

BACKGROUND: Calcium/calmodulin-dependent protein kinase IV (CaMKIV) controls activity-dependent gene transcription by regulating the activity of the cyclic AMP response element binding protein (CREB). This signaling pathway is involved in gating emotional responses in the CNS but previous studies di...

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Detalles Bibliográficos
Autores principales: Schneider, Miriam, Spanagel, Rainer, Zhang, Sheng-Jia, Bading, Hilmar, Klugmann, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219998/
https://www.ncbi.nlm.nih.gov/pubmed/18053176
http://dx.doi.org/10.1186/1471-2202-8-105

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