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The oxidative stress adaptor p66Shc is required for permanent embryo arrest in vitro
BACKGROUND: Excessive developmental failure occurs during the first week of in vitro embryo development due to elevated levels of cell death and arrest. We hypothesize that permanently arrested embryos enter a stress-induced "senescence-like" state that is dependent on the oxidative stress...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220003/ https://www.ncbi.nlm.nih.gov/pubmed/18047664 http://dx.doi.org/10.1186/1471-213X-7-132 |