Cargando…
Time-dependent Outward Currents through the Inward Rectifier Potassium Channel IRK1 : The Role of Weak Blocking Molecules
Outward currents through the inward rectifier K(+) channel contribute to repolarization of the cardiac action potential. The properties of the IRK1 channel expressed in murine fibroblast (L) cells closely resemble those of the native cardiac inward rectifier. In this study, we added Mg(2+) (0.44–1.1...
Autor principal: | Ishihara, Keiko |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2220059/ https://www.ncbi.nlm.nih.gov/pubmed/9041451 |
Ejemplares similares
-
[K+] dependence of polyamine-induced rectification in inward rectifier potassium channels (IRK1, Kir2.1)
Publicado: (1996) -
IRK1 Inward Rectifier K(+) Channels Exhibit No Intrinsic Rectification
por: Guo, Donglin, et al.
Publicado: (2002) -
Mechanism of the Voltage Sensitivity of IRK1 Inward-rectifier K(+) Channel Block by the Polyamine Spermine
por: Shin, Hyeon-Gyu, et al.
Publicado: (2005) -
Interaction Mechanisms between Polyamines and IRK1 Inward Rectifier K(+) Channels
por: Guo, Donglin, et al.
Publicado: (2003) -
Pore Block versus Intrinsic Gating in the Mechanism of Inward Rectification in Strongly Rectifying Irk1 Channels
por: Guo, Donglin, et al.
Publicado: (2000)