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Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage

BACKGROUND: Vaccination of neonates is generally difficult due to the immaturity of the immune system and consequent higher susceptibility to tolerance induction. Genetic immunization has been described as an alternative to trigger a stronger immune response in neonates, including significant Th1 po...

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Detalles Bibliográficos
Autores principales:	Pelizon, Ana Cláudia, Martins, Douglas R, Zorzella, Sofia FG, Trombone, Ana Paula F, Lorenzi, Júlio CC, Carvalho, Robson F, Brandão, Izaíra T, Coelho-Castelo, Arlete AM, Silva, Célio L, Sartori, Alexandrina
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222600/ https://www.ncbi.nlm.nih.gov/pubmed/18047644 http://dx.doi.org/10.1186/1479-0556-5-12

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