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Motavizumab, A Neutralizing Anti-Respiratory Syncytial Virus (Rsv) Monoclonal Antibody Significantly Modifies The Local And Systemic Cytokine Responses Induced By Rsv In The Mouse Model

Motavizumab (MEDI-524) is a monoclonal antibody with enhanced neutralizing activity against RSV. In mice, motavizumab suppressed RSV replication which resulted in significant reduction of clinical parameters of disease severity. We evaluated the effect of motavizumab on the local and systemic immune...

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Detalles Bibliográficos
Autores principales:	Mejías, Asunción, Chávez-Bueno, Susana, Raynor, Martin B, Connolly, John, Kiener, Peter A, Jafri, Hasan S, Ramilo, Octavio
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222633/ https://www.ncbi.nlm.nih.gov/pubmed/17961258 http://dx.doi.org/10.1186/1743-422X-4-109

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