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Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade

Influenza viruses replicate within the nucleus of infected cells. Viral genomic RNA, three polymerase subunits (PB2, PB1, and PA), and the nucleoprotein (NP) form ribonucleoprotein complexes (RNPs) that are exported from the nucleus late during the infectious cycle. The virus-induced Raf/MEK/ERK (MA...

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Detalles Bibliográficos
Autores principales:	Marjuki, Henju, Yen, Hui-Ling, Franks, John, Webster, Robert G, Pleschka, Stephan, Hoffmann, Erich
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222635/ https://www.ncbi.nlm.nih.gov/pubmed/18053252 http://dx.doi.org/10.1186/1743-422X-4-134

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