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Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies
BACKGROUND: 14-3-3σ is a p53-mediated cell-cycle inhibitor in epithelial cells. The expression of 14-3-3σ is frequently altered in cancers of epithelial origin associated with altered DNA methylation. Since its involvement in a non-epithelial tumor is unknown, we examined 14-3-3σ expression in patie...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222637/ https://www.ncbi.nlm.nih.gov/pubmed/18036248 http://dx.doi.org/10.1186/1471-2407-7-217 |