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The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G
BACKGROUND: The HIV-1 accessory protein known as viral infectivity factor or Vif binds to the host defence factor human APOBEC3G (hA3G) and prevents its assembly with viral particles and mediates its elimination through ubiquitination and degradation by the proteosomal pathway. In the absence of Vif...
Autores principales: | Miller, James H, Presnyak, Vlad, Smith, Harold C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222665/ https://www.ncbi.nlm.nih.gov/pubmed/18036235 http://dx.doi.org/10.1186/1742-4690-4-81 |
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