Cargando…
Epigenetic regulation of RhoB loss of expression in lung cancer
BACKGROUND: RhoB is down-regulated in most lung cancer cell lines and tumor tissues when compared with their normal counterparts. The mechanism of this loss of expression is not yet deciphered. METHODS: Since no mutation has been reported in the RhoB sequence, we investigated the epigenetic regulati...
Autores principales: | Mazières, Julien, Tovar, Daniel, He, Biao, Nieto-Acosta, Jacobo, Marty-Detraves, Claire, Clanet, Carine, Pradines, Anne, Jablons, David, Favre, Gilles |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222678/ https://www.ncbi.nlm.nih.gov/pubmed/18047684 http://dx.doi.org/10.1186/1471-2407-7-220 |
Ejemplares similares
-
The RAS‐related GTPase RHOB confers resistance to EGFR‐tyrosine kinase inhibitors in non‐small‐cell lung cancer via an AKT‐dependent mechanism
por: Calvayrac, Olivier, et al.
Publicado: (2016) -
RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor
por: Médale-Giamarchi, Claire, et al.
Publicado: (2013) -
Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation
por: Chinestra, Patrick, et al.
Publicado: (2014) -
The RhoB small GTPase in physiology and disease
por: Vega, Francisco M., et al.
Publicado: (2016) -
Expression Loss and Revivification of RhoB Gene in Ovary Carcinoma Carcinogenesis and Development
por: Liu, Yingwei, et al.
Publicado: (2013)