Breast cancer risk in mothers of twins.

The risk of breast cancer associated with delivering a twin birth was examined in a population-based nested case-control study of nearly 4800 Swedish women with breast cancer and 47000 age-matched control subjects. All were aged less than 50 years and parous. After adjustment for age at first birth...

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Autores principales: Murphy, M. F., Broeders, M. J., Carpenter, L. M., Gunnarskog, J., Leon, D. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222743/
https://www.ncbi.nlm.nih.gov/pubmed/9083344
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author Murphy, M. F.
Broeders, M. J.
Carpenter, L. M.
Gunnarskog, J.
Leon, D. A.
author_facet Murphy, M. F.
Broeders, M. J.
Carpenter, L. M.
Gunnarskog, J.
Leon, D. A.
author_sort Murphy, M. F.
collection PubMed
description The risk of breast cancer associated with delivering a twin birth was examined in a population-based nested case-control study of nearly 4800 Swedish women with breast cancer and 47000 age-matched control subjects. All were aged less than 50 years and parous. After adjustment for age at first birth and parity, a 29% reduction in breast cancer risk was observed in mothers of twins relative to those who were not (odds ratio = 0.71, 95% confidence interval 0.55-0.91). These results provide evidence that women who bear twins are at reduced risk of breast cancer, one explanation for which may be their unusual levels of hormonal exposure.
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spelling pubmed-22227432009-09-10 Breast cancer risk in mothers of twins. Murphy, M. F. Broeders, M. J. Carpenter, L. M. Gunnarskog, J. Leon, D. A. Br J Cancer Research Article The risk of breast cancer associated with delivering a twin birth was examined in a population-based nested case-control study of nearly 4800 Swedish women with breast cancer and 47000 age-matched control subjects. All were aged less than 50 years and parous. After adjustment for age at first birth and parity, a 29% reduction in breast cancer risk was observed in mothers of twins relative to those who were not (odds ratio = 0.71, 95% confidence interval 0.55-0.91). These results provide evidence that women who bear twins are at reduced risk of breast cancer, one explanation for which may be their unusual levels of hormonal exposure. Nature Publishing Group 1997 /pmc/articles/PMC2222743/ /pubmed/9083344 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Murphy, M. F.
Broeders, M. J.
Carpenter, L. M.
Gunnarskog, J.
Leon, D. A.
Breast cancer risk in mothers of twins.
title Breast cancer risk in mothers of twins.
title_full Breast cancer risk in mothers of twins.
title_fullStr Breast cancer risk in mothers of twins.
title_full_unstemmed Breast cancer risk in mothers of twins.
title_short Breast cancer risk in mothers of twins.
title_sort breast cancer risk in mothers of twins.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222743/
https://www.ncbi.nlm.nih.gov/pubmed/9083344
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AT broedersmj breastcancerriskinmothersoftwins
AT carpenterlm breastcancerriskinmothersoftwins
AT gunnarskogj breastcancerriskinmothersoftwins
AT leonda breastcancerriskinmothersoftwins

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