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Helical Structure and Packing Orientation of the S2 Segment in the Shaker K(+) Channel
Six transmembrane segments, S1–S6, cluster around the central pore-forming region in voltage-gated K(+) channels. To investigate the structural characteristics of the S2 segment in the Shaker K(+) channel, we replaced each residue in S2 singly with tryptophan (or with alanine for the native tryptoph...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222899/ https://www.ncbi.nlm.nih.gov/pubmed/10051517 |