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Mutations in the S4 Region Isolate the Final Voltage-dependent Cooperative Step in Potassium Channel Activation
Charged residues in the S4 transmembrane segment play a key role in determining the sensitivity of voltage-gated ion channels to changes in voltage across the cell membrane. However, cooperative interactions between subunits also affect the voltage dependence of channel opening, and these interactio...
Autores principales: | Ledwell, Jennifer L., Aldrich, Richard W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222902/ https://www.ncbi.nlm.nih.gov/pubmed/10051516 |
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