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Rapid and Direct Effects of pH on Connexins Revealed by the Connexin46 Hemichannel Preparation
pH is a potent modulator of gap junction (GJ) mediated cell–cell communication. Mechanisms proposed for closure of GJ channels by acidification include direct actions of H(+) on GJ proteins and indirect actions mediated by soluble intermediates. Here we report on the effects of acidification on conn...
Autores principales: | Brady Trexler, E., Bukauskas, Feliksas F., Bennett, Michael V.L., Bargiello, Thaddeus A., Verselis, Vytas K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222913/ https://www.ncbi.nlm.nih.gov/pubmed/10228184 |
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