ER Stress-Mediated Apoptosis in a New Mouse Model of Osteogenesis imperfecta

Osteogenesis imperfecta is an inherited disorder characterized by increased bone fragility, fractures, and osteoporosis, and most cases are caused by mutations affecting the type I collagen genes. Here, we describe a new mouse model for Osteogenesis imperfecta termed Aga2 (abnormal gait 2) that was...

Descripción completa

Detalles Bibliográficos
Autores principales: Lisse, Thomas S, Thiele, Frank, Fuchs, Helmut, Hans, Wolfgang, Przemeck, Gerhard K. H, Abe, Koichiro, Rathkolb, Birgit, Quintanilla-Martinez, Leticia, Hoelzlwimmer, Gabriele, Helfrich, Miep, Wolf, Eckhard, Ralston, Stuart H, de Angelis, Martin Hrabé
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222924/
https://www.ncbi.nlm.nih.gov/pubmed/18248096
http://dx.doi.org/10.1371/journal.pgen.0040007

Ejemplares similares

Ejemplares similares