Targeting of Interferon-Beta to Produce a Specific, Multi-Mechanistic Oncolytic Vaccinia Virus

BACKGROUND: Oncolytic viruses hold much promise for clinical treatment of many cancers, but a lack of systemic delivery and insufficient tumor cell killing have limited their usefulness. We have previously demonstrated that vaccinia virus strains are capable of systemic delivery to tumors in mouse m...

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Detalles Bibliográficos
Autores principales: Kirn, David H, Wang, Yaohe, Le Boeuf, Fabrice, Bell, John, Thorne, Steve H
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222946/
https://www.ncbi.nlm.nih.gov/pubmed/18162040
http://dx.doi.org/10.1371/journal.pmed.0040353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222946/
https://www.ncbi.nlm.nih.gov/pubmed/18162040
http://dx.doi.org/10.1371/journal.pmed.0040353

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