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TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle
Members of the TRIpartite interaction Motif (TRIM) family of E3 ligases have been shown to exhibit antiviral activities. Here we report a near comprehensive screen for antiretroviral activities of 55 TRIM proteins (36 human, 19 mouse). We identified ∼20 TRIM proteins that, when transiently expressed...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222954/ https://www.ncbi.nlm.nih.gov/pubmed/18248090 http://dx.doi.org/10.1371/journal.ppat.0040016 |