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TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle

Members of the TRIpartite interaction Motif (TRIM) family of E3 ligases have been shown to exhibit antiviral activities. Here we report a near comprehensive screen for antiretroviral activities of 55 TRIM proteins (36 human, 19 mouse). We identified ∼20 TRIM proteins that, when transiently expressed...

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Detalles Bibliográficos
Autores principales: Uchil, Pradeep D, Quinlan, Brian D, Chan, Wai-Tsing, Luna, Joseph M, Mothes, Walther
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222954/
https://www.ncbi.nlm.nih.gov/pubmed/18248090
http://dx.doi.org/10.1371/journal.ppat.0040016

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